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2018 Preliminary Program

Program for 2017 American Aging Association 46th Annual Meeting and Nathan Shock Centers Pre-Conference Symposium

Friday,  Jun 9th

Pre-Conference Symposium:  Nathan Shock Centre Meeting - Emerging techniques and technologies for basic aging research

9:00 AM - 9:15 AM                                       Salon D

Introductions:  Stephanie Lederman, Felipe Sierra

9:15 AM - 9:30 AM

Meeting Overview:  Steven Austad

9:30 AM - 9:50 AM

Matt Kaeberlein, University of Washington, Microfluidic technologies to

study mechanisms of aging

9:50 AM - 10:10 AM

Daniel Promislow, University of Washington,  Metabolomics

and the Systems Biology of Aging

10:10 AM - 10:30 AM

George Sutphin, The Jackson Lab, JACT Combining Systems and

Comparative Genetics to Identify Novel Molecular Targets for Longevity

and Age-Associated Disease

10:30 AM - 10:50 AM

Catherine Kaczorowski, The Jackson Laboratory

Systems Genetics Identifies Resilience Factors in Cognitive Aging

10:50 AM - 11:20 AM

Coffee break

11:20 AM - 11:40 AM

Esperanza Arias, Albert Einstein College of Medicine Mechanism of action of CR in animals and humans.

11:40 AM - 12:00 PM

Laura Santambrogio,  Albert Einstein College of Medicine Aging-associated protein carbonylation, glycation, lipoxidation and their effects on cellular proteostasis and immunosenecence

12:00 PM - 12:20 PM

Willard Freeman, University of Oklahoma Health Sciences Center

Use of next generation epigenomic approaches to study the role of DNA

methylation in aging

12:20 PM - 12:40 PM

Jonathan Wren, Oklahoma Medical Research Foundation

Transcriptional changes with age - taking advantage of large, public

datasets to answer important questions

12:40 PM - 1:30 PM Salon C

Buffet Lunch

1:30 PM - 1:50 PM Salon D

Marty Javors, PhD and Al Fisher, MD, PhD, University of Texas Health

Science Center, San Antonio   Searching for Mechanisms of Aging

Interventions Using the Bioanalytical Pharmacology Core

1:50 PM - 2:10 PM

Adam Salmon, Ph.D. and Jim Nelson, Ph.D., University of Texas Health

Science Center, San Antonio  Testing Rapamycin to Extend Marmoset

Longevity Using the Aging Animal Models and Longevity Assessment

Core  

2:10 PM - 2:30 PM

Steven Austad, Ph.D., University of Alabama, Birmingham

What can a mitochondrial-nuclear exchange mouse do for me?

2:30 PM - 2:50 PM

David Allison, Ph.D. University of Alabama, Birmingham

The Value of Owning Our Statistical Errors in Aging Research: From the

Curious to the Humorous

2:50 PM

Wrap-up discussion

3:00 PM

Adjourn

3:30 PM – 4 PM                                         Salon D                      

Trainee Chapter Meeting: Chair, R. Michael Anson, Community College of Baltimore County

4 PM – 5:30 PM

4:00 - 4:30 PM



4:30 - 5-30PM

Career Development Roundtable and Networking Forum:

Chair, Christiaan Leeuwenburgh, University of Florida, Institute on Aging. Outlook for federal and foundation support for biomedical research and research education training and various prospective career opportunities for PhD and Post-Doctoral Students

 .

Panel Participants:

Helen Griffiths (Surrey UK).

Felipe Sierra (NIH)

Stephanie Lederman (AFAR)

Bita Nakhai (NIH/NIA)


Salon D and E Foyer

Poster Set-Up and Registration

6:30 PM – 10 PM                    Salon D Foyer

46th AGE Conference Registration and Opening Reception

Introduction

Opening Reception

Saturday  Jun 10th


8:00 - 8:45 AM Salon D

Keynote address: Sarah Harper PhD, University of Oxford, Director of the Oxford Institute of Population Ageing (to be delivered via Skype)

8.45 – 10:45 AM


8:45 - 9:15 AM


9:15 - 9:45 AM


9:45 - 10:15 AM


10:15 - 10:45 AM

Session 1:  Cell senescence…and after.  Chair: Christian Sell Co-Chair: Helen Griffiths


Kirkland J, Kogod Center on Aging, Mayo Clinic, Cell senescence and the phenotypes of ageing.


Campisi J Buck Institute for Research on Aging Linking Mitochondrial Dysfunction and Senescence.


Ben-Porath I Hebrew University-Hadassah Medical School, Jerusalem, Israel, Effects of p16Ink4a expression and senescence on tissue function


Gil J MRC London Institute of Medical Sciences, Imperial College London The SASP: Connecting senescence with inflammation.

10:45-11.00 AM

Coffee Break and Networking

11.00 AM – 12:40 PM Concurrent Panels


                                                       Salon D

11:00 - 11:15AM


11:15 - 11:30 AM


11:30 - 11:45 AM

11:45 AM - 12:00PM


12:00 - 12:15 PM


12:15 - 12:30                                                  

 Greenpoint/Williamsburg

11:00 - 11:15AM


11:15 - 11:30 AM


11:30 - 11:45 AM



11:45 AM - 12:00PM




12:00 - 12:15 PM


12:15 - 12:30     

Session 2 - selected oral presentations from submitted abstracts Concurrent Panels

Session 2AChair: Elizabeth Ostler (Brighton)

Birch Jodie Newcastle University Institute for Ageing, mTOR inhibition ameliorates senescence independently of the SASP in a mouse model of chronic inflammation

Salmon  Adam University of TX Health Science Center, San Antonio Targeting mTOR to extend longevity in a non-human primate

Ostler  EL University of Brighton Resveralogues: a new mechanism for anti-degeneratives?

Hoffman Jessica University of Alabama at Birmingham The metabolomic consequences of size and age in the companion dog

Quarles Ellen University of Washington, Seattle Short-term rapamycin treatment leads to lasting improvement in cardiac health in aged mice

Panel

Session 2BChair: Karolina Chocian,Oxford, BSRA Korenchevsky speaker

Martin  Nicolas University of Wollongong, Australia Extending maximum lifespan of the honeybee: a new ageing model

Souder  Dylan University of Wisconsin  GSK3b regulates brain energy metabolism

Zambrano Elena Instituto Nacional de Ciencias Médicas y Nutrición SZ  Impaired ischemia induced reperfusion in aged male and female offspring (F1) of obese mothers (MO)

Clarke Geoffrey  University of Texas Health Science Center, San Antonio SW National Primate Research Ctr. Biventricular Cardiac Function Exhibits Sexual Dimorphism in Aging: Magnetic Resonance Imaging (MRI) Results from a Baboon Model 

Chocian Karolina, Oxford Dose-dependent functions for chromatin modifiers in regulating lifespan.

Panel

12:40 – 2:00 PM     Salon D and E Foyer

                                                  Cobble Hill

LUNCH

GeroScience Journal Editorial Board Meeting (by invitation)

1:30 – 3:30 PM


1:30 - 1:50 PM


1:50 - 2::10 PM

2:10 PM - 2:30PM


2:30 - 2:50 PM

:

2:50- 3::30 PM

Session 3New model systems.  Chair: Shelly Buffenstein

Co-Chair: TBA


Patel RC, University of South Carolina, Natural short- and long-lived ecotypes of the microcrustacean Daphnia as models to understand aging.

Smith RK Royal Veterinary College Inflamm-aging and the horse

Valenzano DR Max Planck Institute for Biology of Ageing

The naturally short-lived African turquoise killifish sheds light on the basis of vertebrate aging

Austad SN  University of Alabama at Birmingham

Lessons in longevity from Arctica islandica;


Questions and discussion

3.30 – 4.00 PM

Coffee Break and Networking

4.00 – 4:45 PM Salon D


Session 4: Trainee Chapter Symposium. Chair: Mark McCormick

Co-Chair: Maria Konovalenko

3x15 minute trainee talks

4:45-7 PM  Salon D and E Foyer                     

Poster Session and Reception I (posters # 1 through 28)

7 PM – 10 PM    Greenpoint/Williamsburg                

                                                      Salon D

AGE Board of Directors Meeting


Student Data Blitz Bita Nakhai (NIH/NIA)

Sunday, Jun 11th


9 – 11-00 AM                                  Salon D

9:00 - 9:20 AM

9:20 - 9:40 AM


9:40 - 10:00 AM

10.00 - 11:00 AM


Session 5: What can we learn from progeroid syndromes? Chair: Junko Oshima, Co-Chair: Richard Faragher

Oshima J (University of Washington/Chiba University} Molecular and Cellular Mechanisms of Progeroid Syndromes

Harries LW (University of Exeter) Longevity, genomic plasticity and m RNA processing

Slagboom E (Leiden University Medical Center) Loci and pathways significantly associated with human longevity.

Panel

11.00 – 11.30                Salon D and E Foyer

Coffee Break and Networking

11:30 AM - 12:30 PM Concurrent Panels

                    

                                                 Salon D

11:30 – 11:45 AM


11:45 AM - 12:00 PM



12:00 - 12:15 PM


12:15- 12:30 PM


                                       Greenpoint/Williamsburg


11:30 – 11:45 AM


11:45 AM - 12:00 PM


12:00 - 12:15 PM


12:15- 12:30 PM

Session 6 - selected oral presentations from submitted abstracts Concurrent Panels

Session 6AChair: Matthew Campbell, University of Wisconsin

Campbell Matthew:  University of Wisconsin   Intermittent treatment with SS-31 preserves exercise tolerance of aging mice.

Hadad  Niran University of Oklahoma Health Science Ctr.      Caloric-restriction Prevents Age-associated Epigenetic Changes in the Aging Brain

Jin  Kelly:  University of Washington, Seattle  Metabolomics of lifespan extension in calorically restricted fruit flies

Labunskyy, Vyacheslav Boston University. Adaptive aneuploidy as a model to study the role of ER stress resistance in aging

Session 6BChair: Helen Griffiths, Surrey, UK

McCormick Mark  Buck Institute  Gene-gene interactions in replicative lifespan in S. cerevisiae

Logan Sreeathi University of Oklahoma Health Science Ctr.  Role of IGF-1 in Astrocyte Mitochondrial Metabolism in Brain Aging

Parks Eileen Universituy of Oklahoma Health Science Ctr. The impact of reduced neurosterioids in Cognitive Aging

Griffiths Helen R:  Surrey     Oxidised lipids are increased in patients with dementia and affect miR expression by microvascular endothelial cells


12.30 – 2.00 PM                                 Salon D

Denham Harman Award Lecture and Luncheon

Kelvin J. A. Davies, Leonard Davis School of Gerontology, Univ. of So Calif.(selected by Awards Committee in Spring 2017) " From the Oxygen Paradox to Adaptive Homeostasis: the Ruminations of an Aging Free Radical"

2.00PM – 4.00 PM



2:00 - 2:20 PM


2:20 - 2:40 PM


2:40 - 3:00 PM


3:00 - 3:20 PM


3:20 - 4:00 PM

Session 7:  Ethics and communication panel (sponsored by the Glenn Foundation)

Chair: Richard Faragher


Mark R. Collins (Glenn Foundation)


Pat Dade (Cultural Dynamics, UK) Marketer & values based change consultant


Sue Armstrong Journalist and author


Roundtable discussion

4.00 – 4:30 Salon D and E Foyer

Coffee Break and Networking

4:30 – 5:30 PM Salon D

AGE General Membership Meeting

5:30 PM - 8 PM                     Salon D and E Foyer

Poster Session and Reception II

(posters # 29 through 56)

8 PM - midnight

Trainee Chapter Social

Monday June 12th


8:00 - 9:50 AM                                      Salon D


8:00 - 8:15 AM


8:15 - 8:30 AM


8:30 - 8:45 AM



8:45 - 9:00 AM


9:00 - 9:15 AM

9:15 - 9:30 AM


9:30 - 9:50 AM

Session 8: Chair: Arlan Richardson University of Oklahoma Health Science Ctr

Moore Darcie University of Wisconsin Age-specific alteration of the asymemetric segregation of cellular cargoes during mitosis in adult neural stem cells.

Freeman Willard University of Oklahoma Health Science Center Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging

Curran Sean University of Southern California Mitochondrial ALH-6 is essential for sperm quality and regulates male reproductive senescence

Nathanielsz Peter University of Wyoming Texas Biomedical Research Inst.  Mechanisms responsible for the age-related fall in circulating cortisol that begins in early baboon adult life

Westbrook Reyhan Johns Hopkins  Chronic Inflammation-related Metabolomic Profile Discovery in The interleukin 10tm1Cgn mouse

Richardson Arlan University of Oklahoma Health Science Center Role of Necroptosis in Aging and Age-Associated Inflammation

Panel

9:50 – 11:50

9:50 - 10:10 AM


10:10 - 10:30 AM

10:30 - 10:50 AM

10:50 - 11:10 AM


11:10 - 11:50 AM

Session 9: Inflammation, intervention and immunosenescence.

Chair: Janko Nikolich-Zugich Co-Chair: TBA

Lord J (University of Birmingham) Correcting signaling dysregulation in neutrophils and improving immunity in older adults.

Smithey M (University of Arizona, Arizona Center on Aging) From mice to men: translating discoveries in immunosenescence.

Simpson RJ (Texas) What’s the link between exercise, inflammation

and  immunosenescence?

Dunn-Walters D (Surrey) B cell repertoire - what does it tell us about immune senescence


Panel

11:50-12.10            Salon D and E Foyer

Coffee Break and Networking

12.10-1:10                                 Salon D


Session 10: Special Lecture- James Joseph Address

Giulio Pasinetti, MD PhD Icahn School of Medicine at Mount Sinai (selected by Awards Committee Spring 2017) From Responsible Nutrition to Molecular Mechanisms in the Promotion of Age-related Psychological and Cognitive Health

1:10-1:30 PM

Awards Ceremony:  Outstanding Service Award, Nancy Nadon, Student Awards and Close of Meeting




Policy on Video and Photography

This is a public meeting, however, we ask that you refrain from recording or taking photographs of presentations or posters without prior consent from the presenters and the conference staff. While we also encourage the use of social media during the conference, we ask that you not take any images or post any unpublished information.

We appreciate your cooperation.