Post on our job board for $50/week (free posting for AGE members posting openings in their own academic/non-profit lab)! Postings include advertisement via our twitter account (@americanaging) and for paid postings of 1 month or greater, monthly emails to AGE members. Email Catherine Hornsby (email@example.com) with your ad or for details.
Postdoctoral Fellow – Newman lab
The Newman lab studies how signaling metabolites regulate mechanisms of aging. We seek motivated, creative scientists to carry out projects that span biochemistry to translational applications in a vibrant atmosphere with a physician-scientist mentor.
We focus on how mechanisms of aging are regulated by the ketone body beta-hydroxybutyrate, which is made by the body during fasting, ketogenic diet, and exercise. We use a toolkit of ketone body compounds, diet interventions, and genetic modifications to understand the mechanistic effects of ketone bodies on memory and other phenotypes in normal aging, Alzheimer’s disease models, and delirium models. This work involves a combination of in vitro biochemistry, gene expression and protein analysis, and physiological and behavioral studies in laboratory mice.
· MD and/or PhD in Biology, Chemistry, or related fields
· Strong bench laboratory skills
· Works well in collaborative teams
· Able to successfully manage an independent research project
· Prior experience with mouse husbandry, transgenic mice, and behavioral testing a plus
· Prior experience with PCR, RNAseq, Western blotting, mass spectrometry proteomics and metabolomics, and/or gene editing a plus
About the Buck Institute
Our success will ultimately change healthcare. At the Buck, we aim to end the threat of age-related diseases for this and future generations by bringing together the most capable and passionate scientists from a broad range of disciplines to identify and impede the ways in which we age. We are an independent, nonprofit institution located in Marin County, CA, with the goal of increasing human healthspan, or the healthy years of life. Globally recognized as the pioneer and leader in efforts to target aging—the number one risk factor for diseases including Alzheimer’s, Parkinson’s, cancer, macular degeneration, heart disease, and diabetes—the Buck seeks to help people live better longer. Learn more at https://buckinstitute.org.
NOTE: The funded Postdoc position has been filled. Only candidates who have their own funding will be reviewed at this time.
If you meet the above funding criteria, please apply online by submitting the following required documents (1) your CV, (2) a cover letter with a brief statement of your interests and goals, (3) contact information for 2-3 references who are familiar with your scientific work, and (4) a brief letter of support from your PhD or prior postdoctoral adviser. If you cannot upload the requirements as one PDF file, you may send the required documents to HR via HRRequests@buckinstitute.org.
For information contact Thelma García, PhD: firstname.lastname@example.org.
POSTDOCTORAL SCHOLAR EMPLOYMENT OPPORTUNITY
The Benayoun laboratory (http://gero.usc.edu/labs/benayounlab/) at the USC Leonard Davis School of Gerontology focuses on the study of how aging influences gene regulation, and in return, how modulation of the genomic regulation can influence the aging process. To study this question, we use a unique combination of high-throughput ‘omics’ approaches and experimental validation in primary cultures and vertebrate aging models (e.g. mouse, African turquoise killifish, etc.). The goal of the lab is to discover novel target genes and pathways playing a fundamental role in healthy and pathological aging, while leveraging the power of big data to direct novel experimental interventions.
A key direction in the laboratory is in the study of age-related sex differences in innate immune cells (e.g. macrophages, neutrophils) and inflammation, using the mouse as a model. The laboratory has identified a signature of female-specific changes in aged macrophages and is dissecting potential upstream regulators responsible for female-specific changes. We are seeking a skilled and motivated scientist to join the lab as a postdoctoral fellow and make leading contributions to aging research by deciphering the molecular mechanisms of sex-dimorphism in aging.
Successful candidates should have strong training and publication records, and must be able to learn and work independently, yet collaborate effectively with students and staff within the lab. The ideal candidate will have training in experimental biology, with an emphasis on mouse knowledge. Previous experience in experimental genomics (e.g. ChIP-seq, RNA-seq, ATAC-seq), steroid hormone biology, and/or immunology are highly desirable. Candidates should have, or will soon receive, a Ph.D. or equivalent diploma in molecular and cellular biology, immunology, genetics, or a relevant subject area.The successful candidate will work closely with the PI. Extensive training will be available in all areas of highly impactful projects.
Applicants should send a resume, a cover letter and career goals, and contact information for at least 3 references to the PI (Dr. Benayoun; bbenayou[at]usc.edu).
NEW POSITION OPENING for Research Associate II
University of Alabama Birmingham
Department of Cellular, Developmental and Integrative Biology
PI: Constanza Cortes (Assistant Professor)
Salary Range: $27000-49000 (based on experience)
Position will remain open until filled
The newly established Cortes lab (https://sites.uab.edu/cjcortes/) specializes in the study of healthy brain aging and age-associated neurodegenerative diseases, with a focus on Alzheimer’s disease. We utilize transgenic mice to examine the contribution of skeletal muscle metabolism to brain aging and age-associated neurodegenerative diseases. We are looking for a detail-oriented and self-motivated research associate to join our team.
The individual must be detailed oriented, take initiative and have professional accountability. Well-developed writing, communication, interpersonal, and organizational skills are required. Individual must be able to work independently and within a team environment.
Minimum Requirements: Previous mouse experience is a must, including high proficiency at animal handling and management. Candidates should have a bachelor’s degree in Life Science/ Biomedical Sciences or higher.
Qualifications: primary cell culture (neurons and/or myoblasts) and basic molecular biology techniques including PCR, gel electrophoresis and immunoblotting. Experience in immunohistochemistry, immunocytochemistry, sectioning, and microscopy would be an advantage. Ample opportunities to acquire new knowledge/skills exist.
Work Performed:Maintain, examine and perform extensive behavioral and intervention work in mice that model neurological diseases and healthy aging. Coordinate specific experimental projects that utilize mice in the determination of mechanisms of neurodegeneration and the identification of novel therapies to treat neurological diseases. Perform or acquire training to perform minor surgical procedures on mice, including intraperitoneal, stereotactic brain and tail-vein injections. Perform or acquire training to perform culture of primary neurons and primary myoblasts. Prepare tissue and specimens from mice for complex procedures, including microscopy and immunoblotting, and devise experimental techniques for tests and analyses. Oversee behavioral evaluation of mice for motor function, neurological impairment, and cognition / anxiety. Evaluate and interpret collected data and prepare reports and analyses setting forth progress, adverse trends and appropriate recommendations or conclusions. Confer with principal investigator in determining specific experiments to be included in the research protocol and to discuss the interpretation of results. Supervise lower level personnel in mouse maintenance as well as laboratory techniques and procedures. Perform other related duties incidental to the work described herein.
Interested and qualified applicants should apply directly at UAB Portal: https://uab.taleo.net/careersection/ext/jobdetail.ftl?job=T64255
posted August 10, 2019
PhD or MD Junior Faculty Position
The New England Centenarian Study
The internationally renowned New England Centenarian Study (www.bumc.bu.edu/centenarian) is recruiting for a PhD or MD Junior Faculty Position within the Section of Geriatrics and the Department of Medicine based at Boston Medical Center and the Boston University School of Medicine. Four years of funding from the NIH/NIA assures 75% time for the MD or 100% time for the PhD set aside for research. The remaining 25% time for the MD will be for inpatient and outpatient clinical geriatrics. For prospective PhDs, please note that this is a dry-lab environment (e.g epidemiology) and if you are doing wet-lab research, you will need to come as a Principal Investigator with grant(s) supporting that work.
The ideal candidate will have a strong track record in and passion for epidemiological research or basic research relevant to the study of exceptional longevity and healthy aging. There will be mentoring and environmental support for academic growth and the expectation of development of a unique research niche and eventual independent funding. Note that a special interest in Cancer is a plus (hint hint).
Boston Medical Center is a 567-bed academic medical center located in Boston’s historic South End and it is the region’s safety net health care provider with a culturally rich and diverse patient population. The hospital is the primary teaching affiliate for Boston University School of Medicine. The Geriatrics Section (http://www.bmc.org/geriatrics.htm) prides itself as an exceptional model of interdisciplinary care across all sites of care involving 30 physician and advanced practice nursing faculty as well as multiple other inter-professional providers in a collegial, highly respectful and collaborative practice.
Please email your cover letter and CV to:
Thomas Perls MD, MPH
Boston University School of Medicine is an Affirmative Action/Equal Opportunity Employer
POSTDOCTORAL ASSOCIATE POSITION
TEXAS PREGNANCY AND LIFE COURSE HEALTH CENTER. SAN ANTONIO, TEXAS
FROM WOMB TO TOMB: Developmental Programming, Nutrition and Behavior in the Nonhuman Primate
FROM WOMB TO TOMB: Developmental Programming, Nutrition and Behavior in the Nonhuman Primate
A Postdoctoral Associate Position is available on a 4-year National Institute of Aging U19: Womb to Tomb: Developmental Programming and Aging Interactions in Primates.
Start date: January 1, 2019 (negotiable) Salary: NIH Postdoctoral Stipend Range
The U19 evaluates interactive mechanisms of normal aging and developmental programming with longitudinal life course studies in a well-characterized nonhuman primate model.
The position involves work that seeks to determine effects of normal, low, and a high plane of maternal nutrition on offspring brain function using in vivo behavioral testing of learning and cognition as well as studies on alterations in brain structure and differentially expressed genes in an extensive archive of baboon brains across the life course. We will seek epigenetic signatures that alter gene expression and protein translation. Intervention studies will be conducted to alter the rate of aging. All studies involve equal numbers of males and females.
Post-doctoral candidate: We are looking to appoint a dynamic and highly self motivated postdoctoral fellow with a doctoral degree from any scientific field to join this program for two years with potential for a further two years. This position is suitable for a first or second post-doctoral position.
We seek a candidate with experience with some or all the following experimental approaches: in vivo behavioral testing, gene expression analysis, in situ hybridization, protein expression analysis (Western, immunohistochemistry), telemetric recordings of movement. Knowledge and experience in one or more of the following fields will be an advantage: developmental programming, obesity, type 2 diabetes, metabolic syndrome, nutrition, primate behavior, and animal models.
A major goal is to train the successful candidate to become a future leader in programming and aging research.
TPLH is committed to providing educational, employment, and enrichment opportunities for members of underrepresented groups. Women, individuals from traditionally disadvantaged groups, and individuals with disabilities are encouraged to apply.
Contact: Peter Nathanielsz (email@example.com) with a detailed CV and cover letter outlining experience and interests and names of three references who we may contact. To obtain insight into our behavioral program, interested applicants might also like to contact Dr. Hillary Huber, a senior postdoctoral member and team-leader responsible for behavioral aspects of our program. Her email is firstname.lastname@example.org. The work she has been involved in can be accessed on PubMed with the terms Huber HF and baboon.
Molecular & Cellular Biology
University of Arizona
Apply online at: https://uacareers.com/postings/31921
Position Summary. A postdoctoral position is available in the Sutphin Lab to study the role of kynurenine metabolism in aging and age-associated disease. The Sutphin Lab uses a combination of systems and comparative genetics to identify novel genetic and environmental factors capable of influencing longevity and healthspan and characterize their molecular mechanisms of action. We have identified several interventions targeting kynurenine pathway enzymes or metabolites that robustly extend lifespan in C. elegans. A current focus of the lab is to understand the molecular mechanisms through which kynurenine pathway manipulation affects longevity using both C. elegans and mice as model systems. We are further evaluating these interventions as treatments for specific age-associated diseases including Alzheimer’s disease, cardiovascular disease, and stroke. This position will involve developing, managing, and executing project(s) focused on the mechanisms linking kynurenine metabolism to aging.
Qualifications. We seek applicants who are independent, hard-working, intellectually curious, and ambitious. We offer a stimulating, interactive, and nurturing environment with numerous opportunities for career development. The successful candidate will be responsible for designing, planning, and conducting experiments using C. elegans and mice, collecting and analyzing data, writing peer reviewed publications, writing fellowship and grant applications, attending scientific conferences to present data, and mentoring students in the laboratory. Required qualifications include a PhD in life sciences or related field.
University of Arizona. Outstanding UA benefits include health, dental, vision, and life insurance; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; access to UA recreation and cultural activities; and more! The University of Arizona has been listed by Forbes as one of America’s Best Employers in the United States and WorldatWork and the Arizona Department of Health Services have recognized us for our innovative work-life programs. For more information about working at the University of Arizona and relocation services, please click here.
The Lamming Laboratory in the Department of Medicine at the University of Wisconsin-Madison (http://lamminglab.org) is looking to hire a postdoctoral researcher with graduate research experience in cell biology, molecular biology, and/or electrophysiology to work on a newly funded R01 exploring the potential of geroprotectors as interventions in established and novel late-onset models of Alzheimer's disease. The candidate will join an exciting research environment investigating the molecular physiology of aging, with an emphasis on understanding how the dietary and pharmaceutical manipulation of nutrient signaling pathways (e.g. mTOR, insulin/IGF-1) can promote health and longevity. The candidate will be jointly mentored with Dr. Matthew Merrins, whose laboratory utilizes imaged-based sensors to probe metabolism at the level of the single cell.
Email cover letter and CV to email@example.com.
NEW POSITION OPENING for POSTDOCTORAL FELLOW
National University of Singapore
Department of Physiology
Assistant Professor: TSAI, Shih-Yin’s laboratory
Annually Salary ranges from $S50,000 to $S72,000.
We seek an enthusiastic and self-motivated postdoctoral fellow to join our team (http://medicine.nus.edu.sg/phys/lab/TsaiSY_Lab/Index.html). Research in the Aging and Metabolism aims to identify the cell-intrinsic mechanism and extracellular factors that hasten muscle function and mass during aging. We utilize genetically modified mouse models and to pinpoint the crucial effectors of muscle growth signalling pathways that could potentially be targeted for therapeutic intervention in elderly suffers from sarcopenia.
Interested and qualified applicants please send an email their curriculum vitae, including methods that the applicant has mastered, a cover letter outlining their research interests, soft copy of the first-authorship publication, and contact information for at least three references to Miss Shu-Wen Koh at firstname.lastname@example.org
NEW POSITION OPENING for Research Associate
National University of Singapore
Department of Physiology
Assistant Professor: TSAI, Shih-Yin’s laboratory
Annually Salary ranges from $S30,000 to $S56,000.
We seek a detail-orientated and self-motivated research associate to join our team (http://medicine.nus.edu.sg/phys/lab/TsaiSY_Lab/Index.html). Research in the Aging and Metabolism aims to identify the cell-intrinsic mechanism and extracellular factors that hasten muscle function and mass during aging. We utilize genetically modified mouse models and to pinpoint the crucial effectors of muscle growth signaling pathways that could potentially be targeted for therapeutic intervention in elderly suffers from sarcopenia. Work with and handle laboratory mice daily.
Interested and qualified applicants should email their curriculum vitae, cover letter outlining their research experience and methods that the applicant has mastered, and contact information for at least three references to Miss Shu-Wen Koh at email@example.com
posted June 9, 2019
Posting Number: 000065
Position Type: Scientific
Department: Aging & Metabolism - Miller
Job Summary/Basic Function:
This is a mentored position for postdoctoral training. Incumbents at this level plan, design and conduct research experiments, manage research projects, prepare reports and papers for publication and presentation, contribute to grant writing and are encouraged to write applications for fellowships. Further, the candidate will learn the complexities of a research lab management and participate in various lab management responsibilities.
• Ph.D. in biological sciences, physiology, chemistry or other relevant area, M.D., or equivalent.
• Knowledge of the principles and practices of scientific theory and research
• Demonstrates skill in formulating and testing hypotheses
• Ability to conduct scientific research experiments
• Skills in the ability to analyze and summarize data and results
• Writing technical and scientific papers and grants
• Communicate effectively both orally and in writing
• Experience mentoring students and guiding the work of less senior scientists
• Experience managing lab research with progressive competency and leadership
Minimum Degree Required: Doctorate
• Strong background in aging or metabolic research
• Comfort with either human and animal models
• Willingness to mentor
• Willingness to contribute to a team effort
• An interest in some combination of aging, muscle, mitochondria, slowed-aging treatments, metabolism, stable isotopes and proteomics
Regularly required to stand, use manual dexterity, talk or hear; Frequently required to walk and reach with hands and arms; occasionally sit; frequently lift and/or move up to 50 pounds; vision abilities include close vision, color vision, depth perception and ability to adjust focus. Potential exposure to fumes, airborne particles, or rodent dander. May work with toxic, caustic chemicals, radioactive materials, liquid nitrogen, human tissue or blood. Potential risk of electrical shock. Occasional exposure to cold 4C, and/or extreme cold -80C from freezers. Noise level is usually moderate.
To apply, visit https://apptrkr.com/1482269
Copyright ©2017 Jobelephant.com Inc. All rights reserved.
We invite you to join us as a graduate student (Ph.D. or M.D.-Ph.D.) or postdoctoral fellow to study the biology of aging at the world-renowned Barshop Institute. We are the only institution in the US to house both a Nathan Shock Center on the Biology of Aging, which is a grant from the National Institute on Aging that supports basic aging research, as well as an Older Americans Independence Center (often called “Pepper Center”), a grant from the NIA to support translational aging research. We have more than 100 faculty members engaged in various aspects of aging research. Our NIA-funded Training Grant has 4 predoctoral graduate student positions and 4 postdoctoral fellowships available.
This training program for research scientists covers such areas as the genetics of aging, lifespan, and intervention analyses in aging and models of age-related diseases. Focus is on translational-oriented trials in a wide range of animal models, including marmosets, and early-phase clinical studies in human subjects. Trainees will participate in programs involving such topics as:
Two post doc positions available in the laboratory of Dr. Paul Robbins, Associate Director of the Institute on the Biology of Aging and Metabolism at the University of Minnesota Medical School.
A post-doctoral position is available in the laboratory of Dr. Paul Robbins, Associate Director of the Institute on the Biology of Aging and Metabolism at the University of Minnesota Medical School. The post-doctoral fellow will be working on characterizing the anti-senescence activity of stem cell EVs and the mechanism of action. The candidate will join an exciting research environment in the newly established Institute on the Biology of Aging and Metabolism and the Department of Biochemistry, Molecular Biology and Biophysics at the University of Minnesota Medical School. The position offers exceptional training in stem cells, extracellular vesicles, aging, age-related diseases, cellular senescence, DNA damage and repair and molecular therapeutics.
Essential Qualifications: PhD in Biochemistry, molecular biology or a related area with specialization in cell signaling pathways or stem cell biology. Experience with EVs is preferred, but not required
Preferred Qualifications: The ideal candidate will have a genuine interest in aging research. He/she will also have experience working on cell signaling, stem cell biology, EVs and/or senescence. Skilled in molecular biology, stem cells and mammalian cell culture, EVs, confocal imaging, bioinformatics and rodent experimentation. Good verbal and written communication skills, the ability to work independently, and an interest in mentoring young scientists.
How to Apply:
Applicants must apply online at: http://www1.umn.edu/ohr/employment/. Click on the appropriate tab under “Search & Apply for Openings”, enter #325610 - stem cell EVs and their mechanisms of action into the “Keywords” field, click the “Search” tab. Applicants should attach a cover letter, curriculum vitae, a description of their research program and a list of 3 potential references. Review of applications will begin immediately and continue until the position is filled.
A post-doctoral position is available in the laboratory of Dr. Paul Robbins, Associate Director of the Institute on the Biology of Aging and Metabolism at the University of Minnesota Medical School. The laboratory is using genetic information from human centenarians to identify pathways important for extending human healthspan. The post-doctoral fellow will be developing assays for identifying drugs targeting these pathways. The candidate will join an exciting research environment in the Department of Biochemistry, Molecular Biology and Biophysics and the newly established Institute on the Biology of Aging and Metabolism at the University of Minnesota Medical School. The position offers exceptional training in aging, age-related diseases, cellular senescence, DNA damage and repair and molecular therapeutics.
Essential Qualifications: PhD in Biochemistry, molecular biology or a related area with specialization in cell signaling pathways, drug development, and cell culture.
Preferred Qualifications: The ideal candidate will have a genuine interest in aging research. He/she will also have experience dissecting signaling pathways of cell growth, differentiation and death and skilled in molecular biology, mammalian cell culture, confocal imaging, bioinformatics and/or rodent experimentation. Also will have good verbal and written communication skills, the ability to work independently, and an interest in mentoring young scientists.
How to Apply:
Applicants must apply online at: http://www1.umn.edu/ohr/employment/. Click on the appropriate tab under “Search & Apply for Openings”, enter # 325611 - identification of drugs for human healthspan into the “Keywords” field, click the “Search” tab. Applicants should attach a cover letter, curriculum vitae, a description of their research program and a list of 3 potential references. Review of applications will begin immediately and continue until the position is filled.
About the Institute:
The new Institute on the Biology of Aging and Metabolism, housed in Nils Hasselmo Hall, is developing safe and effective approaches for promoting healthy aging through an understanding of the basic biological mechanisms that underpin aging as well as identifying early diagnostic biomarkers of unhealthy aging. Examples of the therapeutic approaches we are developing include adult stem cells, biologics, small molecules, nutraceuticals and natural products.
About the Department:
The Department of Biochemistry, Molecular Biology and Biophysics is committed to understanding the molecular mechanisms of metabolic diseases and cancer; developing novel strategies in biocatalysis and biotechnology; and advancing knowledge through structural biology and molecular biophysics. We organize ourselves into research divisions with emphases on Chemical and Structural Biology, Metabolic and Systems Biology, Molecular Biology and Synthetic Biology and Biotechnology. We are housed in new buildings with state-of-the-art research and support facilities.
The University of Minnesota provides equal access to and opportunity in its programs, facilities, and employment without regard to race, color, creed, religion, national origin, gender, age, marital status, disability, public assistance status, veteran status, sexual orientation, gender identity, or gender expression. The University supports the work-life balance of its faculty and especially encourages applications from women and members of under-represented groups.
Background check information:
Any offer of employment is contingent upon the successful completion of a background check. Our presumption is that prospective employees are eligible to work here. Criminal convictions do not automatically disqualify finalists from employment.
About the U of M:
The University of Minnesota, Twin Cities (UMTC), is among the largest public research universities in the country, offering undergraduate, graduate, and professional students a multitude of opportunities for study and research. Located at the heart of one of the nation's most vibrant, diverse metropolitan communities, students on the campuses in Minneapolis and St. Paul benefit from extensive partnerships with world-renowned health centers, international corporations, government agencies, and arts, nonprofit, and public service organizations.
Postdoctoral Research Fellow
Scott Leiser Laboratory, Geriatrics Center, University of Michigan Ann Arbor
Position Summary: Applications are invited for a postdoctoral research position in the laboratory of Scott Leiser at the University of Michigan. Dr. Leiser’s NIH-funded studies focus on the biology of aging, using multiple model organisms to understand how organisms perceive and respond to stress. We are particularly interested in the physiological responses to food and oxygen deprivation (hypoxia), and how these responses affect aging. Our lab utilizes C. elegans, mammalian cells, and mouse models to study conserved pathways of stress response and their role in regulating the aging process. These projects offer the unique opportunity to integrate multiple systems to model the biology of aging.
The University of Michigan is consistently ranked at the top of public research institutions and is a national leader in funding from both the NIH as a whole and the NIA in particular. We have state of the art amenities and are housed in an award-winning new building with access to facilities, equipment and expertise in every area of science. Ann Arbor offers the amenities of a big city with the feel of a college town and proximity to the robust Detroit Metro area. The University provides state-of-the-art lab spaces and access to extensive seminars, workshops, and career development programs in support of long-term career goals. The Leiser lab uses a very collaborative, team-oriented approach to science that is in line with the university as a whole.
Qualifications: A successful candidate should be extremely motivated, with desire and ability to work independently in the context of a team. Candidates with backgrounds or interest in neurobiology, C. elegans biology, and/or aging biology are strongly encouraged to apply. Previous experience in these systems is encouraged, but not necessary. Required qualifications include a Ph.D. or equivalent. Salary will be based on the NIH published postdoctoral stipend levels. The successful candidate will play a key role in experimental design, data collection and analysis, and preparation of oral and scientific reports.
Review of applications will begin immediately until 1-2 positions are filled. Please submit cover letter, CV, and 2-4 reference contacts to Scott Leiser (firstname.lastname@example.org).