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We are pleased to share the recipients of the 2025 GeroScience Outstanding Publication Awards, announced on May 12th during the 53rd Annual Meeting of the American Aging Association (AGE) in Anchorage, Alaska. These awards recognize exceptional research published in GeroScience, and the following individuals have been honored for their outstanding contributions to the field of aging science: GeroScience Outstanding Original Research Paper AwardFIRST PRIZE: Rafal Gulej, PharmD, PhD, Postdoctoral Fellow, University of Oklahoma Health Sciences Center. Rejuvenation of cerebromicrovascular function in aged mice through heterochronic parabiosis: insights into neurovascular coupling and the impact of young blood factors. https://rdcu.be/epiZi SECOND PRIZE: Aung Zaw Zaw Phyo, MPH, MSc with Distinction, PhD, Research Fellow, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia. Sex differences in biological aging and the association with clinical measures in older adults. https://rdcu.be/epiZu THIRD PRIZE: SARAH ASHIQUEALI, Postdoctoral Fellow, Mayo Clinic’s Robert and Arlene Kogod Center on Aging, Rochester, MN.Fisetin modulates the gut microbiota alongside biomarkers of senescence and inflammation in a DSS‑induced murine model of colitis. https://rdcu.be/epi0f FORTH PRIZE: Shunsuke Murata, PhD Guest researcher, Unit of Epidemiology, Institute of Environmental Medicine, Karolinska Institute, Sweden.Blood biomarker profiles and exceptional longevity: comparison of centenarians and non‑centenarians in a 35‑year follow‑up of the Swedish AMORIS cohort. https://rdcu.be/epi0t GeroScience Outstanding Review Paper AwardFIRST PRIZE: William J. Evans, Ph.D., FACSM, FACN Adjunct Professor of Human Nutrition Department of Nutritional Sciences & Toxicology University of California, Berkeley, CA& Adjunct Professor of Medicine, Division of Geriatrics Senior Research Fellow Duke University Medical Center Durham, NC. Sarcopenia: no consensus, no diagnostic criteria, and no approved indication—How did we get here? https://rdcu.be/epi1k SECOND PRIZES: Adam Nyul-Toth, Ph.D.,Assistant Professor, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC.Linking peripheral atherosclerosis to blood–brain barrier disruption: elucidating its role as a manifestation of cerebral small vessel disease in vascular cognitive impairment. https://rdcu.be/epsbb Vittorio Dibello, DDS, MSc, PhD Candidate, “Cesare Frugoni” Internal and Geriatric Medicine and Memory Unit, University of Bari “Aldo Moro”, Bari, Italy & Department of Orofacial Pain and Dysfunction, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam. Oral frailty indicators to target major adverse health-related outcomes in older age: a systematic review. https://rdcu.be/epsbk GeroScience Outstanding Original Research Paper Award- Honorable MentionsYasra Arif et al. Modulation of movement‑related oscillatory signatures by cognitive interference in healthy aging. https://rdcu.be/epsb9 May A. Beydoun et al. Uncovering mediational pathways behind racial and socioeconomic disparities in brain volumes: insights from the UK Biobank study. https://rdcu.be/epsco Leena P. Bharath et al. Everolimus alleviates CD4+ T cell inflammation by regulating autophagy and cellular redox homeostasis. https://rdcu.be/epscr Kyeongho Byun et al. Mild exercise improves executive function with increasing neural efficiency in the prefrontal cortex of older adults. https://rdcu.be/epsc5 Marcelo Borges Cavalcante, et al. Ovarian aging in humans: potential strategies for extending reproductive lifespan reproductive lifespan. https://rdcu.be/epsdw Chiranjib Chakraborty et al. Omicron variant (B.1.1.529) of SARS‑CoV‑2: understanding mutations in the genome, S‑glycoprotein, and antibody‑binding regions. https://rdcu.be/epsei Nikhil N. Chaudhari et al. Increases in regional brain volume across two native South American male populations. https://rdcu.be/epse7 Gagan Deep et al. Circulating small extracellular vesicles as blood‑based biomarkers of muscle health in aging nonhuman primates. https://rdcu.be/epsfo Sarah A. DeVries et al. Immune proteins C1q and CD47 may contribute to aberrant microglia‑mediated synapse loss in the aging monkey brain that is associated with cognitive impairment. https://rdcu.be/epsfD Hillary F. Huber & Hannah C. Ainsworth et al. Comparative lifespan and healthspan of nonhuman primate species common to biomedical research. https://rdcu.be/epsf7 Phoebe Imms et al. Neuroanatomical and clinical factors predicting future cognitive impairment. https://rdcu.be/epsgm Hiroko Isoda et al. Transcriptomics and biochemical evidence of trigonelline ameliorating learning and memory decline in the senescence‑accelerated mouse prone 8 (SAMP8) model by suppressing proinflammatory cytokines and elevating neurotransmitter release. https://rdcu.be/epsgr Hashan S. M. Jayarathne et al. Hypothalamic sex‑specific metabolic shift by canagliflozin during aging. https://rdcu.be/epshm Kylie Kavanagh et al. Long‑term dasatinib plus quercetin effects on aging outcomes and inflammation in nonhuman primates: implications for senolytic clinical trial design. https://rdcu.be/epshA Jeongjin J. Kim et al. Effect of aging and exercise on hTERT expression in thymus tissue of hTERT transgenic bacterial artificial chromosome mice. https://rdcu.be/epshK Setor K. Kunutsor et al. Handgrip strength and risk of cognitive outcomes: new prospective study and meta‑analysis of 16 observational cohort studies. https://rdcu.be/epshP Baoqiang Li et al. Measurements of cerebral microvascular blood flow, oxygenation, and morphology in a mouse model of whole‑brain irradiation‑induced cognitive impairment by two‑photon microscopy and optical tomography: evidence for microvascular injury coherence in the cerebral white matter. https://rdcu.be/epsii Theresa Mau et al. Lower muscle mitochondrial energetics is associated with greater phenotypic frailty in older women and men: the Study of Muscle, Mobility and Aging. https://rdcu.be/epsiA Francesco Morandini & Cheyenne Rechsteiner et al. ATAC‑clock: An aging clock based on chromatin accessibility. https://rdcu.be/epsiO Alexandra Moreira‑Pais et al. A neuromuscular perspective of sarcopenia pathogenesis: deciphering the signaling pathways involved. https://rdcu.be/epsje Johannes T. Neumann et al. Cardiovascular risk prediction in healthy older people. https://rdcu.be/epsji Pontus Plavén‑Sigray et al. Multimodal brain age prediction using machine learning: combining structural MRI and 5‑HT2AR PET‑derived features. https://rdcu.be/epsjn János G Pitter et al. Frailty prevalence in 42 European countries by age and gender: development of the SHARE Frailty Atlas for Europe. https://rdcu.be/epska Zsolt Radak et al. DNA methylation clock DNAmFitAge shows regular exercise is associated with slower aging and systemic adaptation. https://rdcu.be/epsnh Aladdin H. Shadyab et al. The association of leukocyte telomere length with exceptional longevity among older women. https://rdcu.be/epsnD Ninadini Sharma et al. Changes in DNA repair compartments and cohesin loss promote DNA damage accumulation in aged oocytes. https://doi.org/10.1093/humrep/deae108.038 Maxim N. Shokhirev et al. CheekAge: a next‑generation buccal epigenetic aging clock associated with lifestyle and health. https://rdcu.be/epsp3 Michelle M. Sonsalla et al. Acarbose ameliorates Western diet‑induced metabolic and cognitive impairments in the 3xTg mouse model of Alzheimer’s disease. https://rdcu.be/epsqt Mercedes Sotos‑Prieto et al. Plant‑based diets and risk of frailty in community‑dwelling older adults: the Seniors‑ENRICA‑1 cohort. https://rdcu.be/epsq6 Marlene E. Starr et al. Accumulation of γδ T cells in visceral fat with aging promotes chronic inflammation. https://rdcu.be/epsry Ka Ka Ting et al. Vascular senescence and leak are features of the early breakdown of the blood–brain barrier in Alzheimer’s disease models. https://rdcu.be/epsr6 Peter J. Toth et al. Age‑related decline in circulating IGF‑1 associates with impaired neurovascular coupling responses in older adults. https://rdcu.be/epsse Claudia M. Trujillo‑Vargas et al. Immune phenotype of the CD4+ T cells in the aged lymphoid organs and lacrimal glands. https://rdcu.be/epsst Borbála Turcsán et al. Differential behavioral aging trajectories according to body size, expected lifespan, and head shape in dogs. https://rdcu.be/epssS Fabrizio Vecchio et al. Analysis of complexity in the EEG activity of Parkinson’s disease patients by means of approximate entropy. https://rdcu.be/epssY Manlio Vinciguerra et al. Nociceptin/orphanin FQ opioid receptor (NOP) selective ligand MCOPPB links anxiolytic and senolytic effects. https://rdcu.be/epNrp Jordan Weiss et al. Polypharmacy and its association with dementia, Parkinson’s disease, and mortality risk in UK adults: a multistate modeling approach. https://rdcu.be/epNrD Jordan Williamson et al. Sex difference in brain functional connectivity of hippocampus in Alzheimer’s disease. https://rdcu.be/epNrE Yixuan Ye et al. A genome‑wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways. https://rdcu.be/epNrG Akito Yoshiko et al. Association of skeletal muscle oxidative capacity with muscle function, sarcopenia-related exercise performance, and intramuscular adipose tissue in older adults. https://rdcu.be/epNrN Junhong Yu et al. ChatGPT‑estimated occupational complexity predicts cognitive outcomes and cortical thickness above and beyond socioeconomic status among older adults. https://rdcu.be/epNrR Yuge Zhang et al. Do people reach 100 by surviving, delaying, or avoiding diseases? A life course comparison of centenarians and non‑centenarians from the same birth cohorts. https://rdcu.be/epNrS GeroScience Outstanding Review Paper Award-Honorable MentionsPeter Csecsei et al. Mitochondrial dysfunction in long COVID: mechanisms, consequences, and potential therapeutic approaches. https://rdcu.be/epNrT Zhaoli Dai et al. A systematic review of diet and medication use among centenarians and near‑centenarians worldwide. https://rdcu.be/epNrU Victoria Delpino et al. The interplay of aging, adipose tissue, and COVID‑19: a potent alliance with implications for health. https://rdcu.be/epNsk Gabor Mikala et al. Multiple myeloma, a quintessential malignant disease of aging: a geroscience perspective on pathogenesis and treatment. https://rdcu.be/epNsl Emily Nunan et al. Obesity as a premature aging phenotype — implications for sarcopenic obesity. https://rdcu.be/epNsv Pontus Plavén‑Sigray et al. In vivo medical imaging for assessing geroprotective interventions in humans. https://rdcu.be/epNsw Nicole C. Riddle et al. Comparative analysis of animal lifespan. https://rdcu.be/epNsy Samantha J. Russell et al. Post-acute sequelae of SARS-CoV-2 infection (Long COVID) in older adults. https://rdcu.be/epNsI Shengshuai Shan et al. Serine metabolism in aging and age‑related diseases. https://rdcu.be/epNsO Nathalie Sumien et al. The potential of hyperbaric oxygen as a therapy for neurodegenerative diseases. https://rdcu.be/epNsT Marta Zampino et al. Biomarkers of aging in real life: three questions on aging and the comprehensive geriatric assessment. https://rdcu.be/epNs6
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ISSN: 0161-9152 (print version); ISSN: 1574-4647 (electronic version) Springer Netherlands For submission information click here. To subscribe to our "Table of Contents" updates click here. Inquiries please email [email protected] GeroScience is a quarterly, international, peer-reviewed journal that publishes articles related to research in the biology of aging and research on biomedical applications that impact aging. The scope of articles to be considered include evolutionary biology, biophysics, genetics, genomics, proteomics, molecular biology, cell biology, biochemistry, endocrinology, immunology, physiology, pharmacology, neuroscience, and psychology. Articles concerning clinical studies will also be considered if the results relate to underlying biological mechanisms of aging. Such studies should reflect more than issues related to the care and treatment of geriatric patients. Papers concerned with social, economic, and political issues of aging will generally not be considered unless they relate directly to biomedical gerontology. In addition to manuscripts emerging from original research, the journal actively solicits research reviews of important topics in biomedical gerontology. Other types of manuscripts are also acceptable, such as commentaries, debates, and meeting reports. GeroScience is a bi-monthly, international, peer-reviewed journal that publishes articles related to research in the biology of aging and research on biomedical applications that impact aging. The Journal is available online to current Association scientific members. Lay members and student members can purchase online subscriptions for $30 per year. For more information on GeroScience, please review the information at the publisher's site by clicking here. EDITORIAL BOARD
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