Career Opportunities


Career Opportunities at SENS Research Foundation

Posted August 24, 2021

https://www.sens.org/get-involved/work-with-us/

Longevity Therapeutics Opportunities at SENS Research Foundation

SRF is at the center of the rejuvenation biotechnology industry and supports the mission to end age-related disease through Research, Education, and Outreach. Make your career something you can believe in – something that can change the world.

Research Associate / Scientist – Boominathan Lab (MitoSENS)

Job Type: Full-time

Number of Positions: 2

Title: Research Associate/Scientist – Boominathan Lab

Salary: Pay is salaried, commensurate with experience and local rates; typically from $55,000/year.

Qualifications: 

    Bachelor’s/Masters/PhD

    Laboratory experience: 2 years (Preferred)

The Boominathan lab at SENS Research Foundation (www.sens.org) is hiring highly motivated Research Scientists / Associates for a project geared toward translational therapies for mitochondrial dysfunctions. SENS Research Foundation is located in the heart of Silicon Valley (Mountain View, CA) and is close to several premier research organizations and major biotech hubs. Ours is an exciting, cutting-edge non-profit organization dedicated to transforming the way the world treats aging. More detailed information can be found at http://sens.org/research/intramural/allotopic-expression.

The successful candidate will use in vitro, in vivo and stem cell models to address diseases due to mtDNA mutations. This research position is within a small but dynamic group that strives to develop a deep understanding and curative therapies using a gene therapy approach to treat mitochondrial myopathies. Qualified candidates will have a BS/MS in the biological sciences and at least 2 years of relevant work experience. Recent PhDs with an exposure to mitochondria biology will be considered for a Research Scientist position. Duties will include performing wet lab experiments, recording, and analyzing data, and presenting the results in formal meetings every 2-3 months.

The ideal applicant will have experience in tissue culture, microscopy, flow cytometry and molecular biology with an exposure to protein analysis and biochemical assays. Hands on experience working with rodents is highly desirable. Experience working with mitochondria or interest in protein modelling are a big plus, but not required.

Other qualities:

    Problem-solving

    Team player

    Creativity and the ability to think beyond an experiment to envision the path to success

    Capacity to adapt as priorities and requirements change

    Ability to plan and document your work diligently

    Excellent written and verbal communication skills in English

    Positive spirit, a real drive for science

We offer an excellent benefits package including paid vacation and sick leave, fully covered health and dental insurance (inclusive of dependents), an FSA program, and a company-matched 401(k) plan, all of which is offered after a 90-day introductory period. SENS Research Foundation is an equal opportunity employer. We may sponsor a visa for international applicants.

The positions are available now and will be filled as soon as qualified candidates are found. Salary is commensurate with job experience. 

TO APPLY: 

Interested candidates should apply by emailing a cover letter stating their scientific interests and current CV to [email protected]

COVID-19 considerations:

All employees are to follow COVID restrictions, which will lighten as our workplace is vaccinated. All employees are expected to wear PPE. Vaccinating is strongly encouraged.

 

Job Opportunity: Postdoctoral Research Fellow – Catabody Project

Job Type: Full-time

Title: Postdoctoral Research Fellow – Catabody Project

Salary: Pay is salaried, commensurate with experience and local rates; typically around $60,000/year.

Qualifications:

    Doctorate (Preferred)

    Molecular biology: 2 years (Preferred)

    Wet chemistry: 2 years (Preferred)

SENS Research Foundation (SRF) is hiring a postdoctoral research fellow for our Research Center (RC) located in Mountain View, CA. SRF is an exciting, cutting-edge non-profit dedicated to transforming the way the world researches and treats aging. 

More detailed information can be found here.

We seek a postdoctoral fellow to join our small but dynamic immunology team led by Dr. Amit Sharma. The project geared towards developing a novel way to remove abnormal tau aggregation. The project is potentially relevant for developing therapeutic mitigation of normal age-dependent cognitive decline, as well as for tauopathies like Alzheimer’s Disease and Related Disorders. This project involves utilizing enzymatic antibodies to target toxic tau aggregates. As part of the project we will explore ways of delivering antibodies into cells. We will use human iPS derived neuronal cells as a model system to test the catalytic antibodies and confirm tau degradation. The project involves extensive use of cell culture and mice models and involves working with human blood samples, primary human cells, and mice tissue. Duties will include performing wet-lab experiments, recording and analyzing data, and presenting the results in meetings every 2-3 months.

Experience:

    Ph.D. in chemical/biological sciences and substantial bench experience or several years of industry experience

    immunology

    antibody design/production/screening

    general molecular biology techniques (such as quantitative real-time PCR, Western blot, immunofluorescence, ELISA.)

    iPSC culturing and neuronal differentiation

Other qualities:

    Problem-solving

    Team player

    Creativity and the ability to think beyond an experiment to envision the path to success

    Capacity to adapt as priorities and requirements change

    Ability to plan and document your work diligently

    Excellent written and verbal communication skills in English

    Positive spirit, a real drive for science

We offer an excellent benefits package including paid vacation and sick leave, fully covered health and dental insurance (inclusive of dependents), an FSA program, and a company-matched 401(k) plan, all of which is offered after a 90-day introductory period. SENS Research Foundation is an equal opportunity employer. The job offer comes with two years contract with the possibility of an extension. We may sponsor a visa for international applicants.

The position is available now and will be filled as soon as the qualified candidate is found. Salary is commensurate with the job title.

TO APPLY:

Interested candidates should apply by emailing a cover letter and current CV to [email protected]

COVID-19 considerations:

All employees are to follow COVID restrictions, which will lighten as our workplace is vaccinated. All employees are expected to wear PPE. Vaccinating is strongly encouraged.

 

Job Opportunity: Research Associate – Catabody Project

Job Type: Full-time

Title: Research Associate

Salary: Pay is salaried, commensurate with experience and local rates; typically around $55,000/year.

Qualifications:

    Master’s (Preferred)

    Laboratory experience: 1 year (Preferred)

    Wet chemistry: 1 year (Preferred)

SENS Research Foundation (SRF) is hiring a Research Associate for our Research Center (RC) located in Mountain View, CA. SRF is an exciting, cutting-edge non-profit dedicated to transforming the way the world researches and treats age-related diseases. More detailed information can be found at our website: www.sens.org

We seek a Research Associate to join our small but dynamic immunology team led by Dr. Amit Sharma. The project geared towards developing a novel way to remove abnormal tau aggregation. The project is potentially relevant for developing therapeutic mitigation of normal age-dependent cognitive decline, as well as for tauopathies like Alzheimer’s Disease and Related Disorders. This project involves utilizing enzymatic antibodies to target toxic tau aggregates. As part of the project we will explore ways of delivering antibodies into cells. We will use human iPS derived neuronal cells as a model system to test the catalytic antibodies and confirm tau degradation. The project involves extensive use of cell culture and mice models and involves working with human blood samples, primary human cells, and mice tissue. Duties will include performing wet-lab experiments, recording and analyzing data, and presenting the results in meetings every 2-3 months.

The ideal candidate for this full-time position has a Ph.D. in chemical/biological sciences and substantial (or the master’s degree with at least 1-2 years) bench experience, industry experience position is preferred. The candidate must be adaptable, a team player, self-motivated, and interested in problem-solving. Duties will include performing wet-lab experiments, recording and analyzing data, and presenting the results in meetings every 2-3 months.

The ideal candidate must have experience with molecular biology techniques, such as quantitative real-time PCR, Western blot, immunofluorescence, ELISA, microplate readers, and flow cytometry analysis, as well as prior experience performing data analysis and presenting data. Preference will be given to candidates with experience in primary cell culture and PBMC isolation from human blood.

We offer an excellent benefits package including paid vacation and sick leave, fully covered health and dental insurance (inclusive of dependents), an FSA program, and a company-matched 401(k) plan, all of which is offered after a 90-day introductory period. SENS Research Foundation is an equal opportunity employer. The job offer comes with two years contract with the possibility of an extension. We may sponsor a visa for international applicants.

The position is available now and will be filled as soon as the qualified candidate is found. Salary is commensurate with the job title.

TO APPLY:

Interested candidates should apply by emailing a cover letter and current CV to [email protected]

COVID-19 considerations:

All employees are to follow COVID restrictions, which will lighten as our workplace is vaccinated. All employees are expected to wear PPE. Vaccinating is strongly encouraged.

 

Job Opportunity: Postdoctoral Research Fellow – Senescence Immunology

Job Type: Full-time

Title: Postdoctoral Research Fellow – Senescence Immunology

Salary: Pay is salaried, commensurate with experience and local rates; typically around $60,000/year.

Qualifications:

    Doctorate (Preferred)

    Molecular biology: 2 years (Preferred)

    Wet chemistry: 2 years (Preferred)

SENS Research Foundation (SRF) is hiring a postdoctoral research fellow for our Research Center (RC) located in Mountain View, CA. SRF is an exciting, cutting-edge non-profit dedicated to transforming the way the world researches and treats age-related diseases. More detailed information can be found at our website: www.sens.org

We seek a postdoctoral fellow to join our small but dynamic immunology team led by Dr. Amit Sharma for a project geared toward investigating the mechanisms involved in the age-dependent decline in immune surveillance of senescent cells with the aim of finding promising interventions.

There are three main projects currently for the postdoctoral fellow. One of the projects involves characterizing age-dependent phenotypes changes in the of Natural Killer cells and its implication on their ability to eliminate senescent cells in cell culture and mice model. We have identified several unique antigens expressed on the surface of senescent cells. The goal of the second project is to characterize the surface antigens on senescent cells and with the goal of developing CAR-NK cells with therapeutic application. The projects will require validating the CAR-NK cells in cell culture and the mice models of senescence. Senescent cells are known to secrete a unique mixture of proinflammatory cytokines, chemokines and matrix modifying proteins called SASP (Senescence Associated Secretory Phenotype). We have identified several SASP factors that may block immune surveillance by NK cells. The aim of the third project is to develop therapeutic interventions based on removal of these SASP proteins for enhancing immune surveillance of senescent cells in aging and senescence mice model. All these projects involve extensive use of cell culture and mice models and involves working with human blood samples, primary human cells, and mice tissue.

The ideal candidate for this full-time position has a Ph.D. in chemical/biological sciences and substantial bench experience. The candidate must be adaptable, a team player, self-motivated, and interested in problem-solving. The prospective postdoc will work closely with the Primary Investigator (PI) on a couple of projects with the potential of landing senior authorships in research publications resulting from the work. Duties will include performing wet-lab experiments, recording and analyzing data, and presenting the results in meetings every 2-3 months. The candidate also will be encouraged to present their findings in relevant national and international conferences and relevant scientific journals.

The ideal candidate must have experience with molecular biology techniques, such as quantitative real-time PCR, Western blot, immunofluorescence, ELISA, microplate readers, and flow cytometry analysis, as well as prior experience performing data analysis and presenting data. Preference will be given to candidates with experience in primary cell culture and PBMC isolation from human blood.

We offer an excellent benefits package including paid vacation and sick leave, fully covered health and dental insurance (inclusive of dependents), an FSA program, and a company-matched 401(k) plan, all of which is offered after a 90-day introductory period. SENS Research Foundation is an equal opportunity employer. The job offer comes with two years contract with the possibility of an extension. We may sponsor a visa for international applicants.

The position is available now and will be filled as soon as the qualified candidate is found. Salary is commensurate with the job title.

TO APPLY: 

Interested candidates should apply by emailing a cover letter and current CV to [email protected]

COVID-19 considerations:

All employees are to follow COVID restrictions, which will lighten as our workplace is vaccinated. All employees are expected to wear PPE. Vaccinating is strongly encouraged.

 

Job Opportunity: Research Associate – Senescence Immunology

Job Type: Full-time

Title: Research Associate

Salary: Pay is salaried, commensurate with experience and local rates; typically around $55,000/year.

Qualifications:

    Master’s (Preferred)

    Laboratory experience: 1 year (Preferred)

    Wet chemistry: 1 year (Preferred)

SENS Research Foundation (SRF) is hiring a Research Associate for our Research Center (RC) located in Mountain View, CA. SRF is an exciting, cutting-edge non-profit dedicated to transforming the way the world researches and treats age-related diseases. More detailed information can be found at our website: www.sens.org

We seek a Research Associate (RA) to join our small but dynamic immunology team led by Dr. Amit Sharma for a project geared toward investigating the mechanisms involved in the immune surveillance of senescent cells with the aim of finding promising interventions.

There are three main projects currently for the RA. One of the projects involves characterizing age-dependent phenotypes changes in the of Natural Killer cells and its implication on their ability to eliminate senescent cells in cell culture and mice model. We have identified several unique antigens expressed on the surface of senescent cells. The goal of the second project is to characterize the surface antigens on senescent cells and with the goal of developing CAR-NK cells with therapeutic application. The projects will require validating the CAR-NK cells in cell culture and the mice models of senescence. Senescent cells are known to secrete a unique mixture of proinflammatory cytokines, chemokines and matrix modifying proteins called SASP (Senescence Associated Secretory Phenotype). We have identified several SASP factors that may block immune surveillance by NK cells. The aim of the third project is to develop therapeutic interventions based on removal of these SASP proteins for enhancing immune surveillance of senescent cells in aging and senescence mice model. All these projects involves extensive use of cell culture and mice models and involves working with human blood samples, primary human cells, and mice tissue. 

The ideal candidate for this full-time position has a Ph.D. in chemical/biological sciences and substantial (or the master’s degree with at least 1-2 years) bench experience, industry experience position is preferred. The candidate must be adaptable, a team player, self-motivated, and interested in problem-solving. Duties will include performing wet-lab experiments, recording and analyzing data, and presenting the results in meetings every 2-3 months.

The ideal candidate must have experience with molecular biology techniques, such as quantitative real-time PCR, Western blot, immunofluorescence, ELISA, microplate readers, and flow cytometry analysis, as well as prior experience performing data analysis and presenting data. Preference will be given to candidates with experience in primary cell culture and PBMC isolation from human blood.

We offer an excellent benefits package including paid vacation and sick leave, fully covered health and dental insurance (inclusive of dependents), an FSA program, and a company-matched 401(k) plan, all of which is offered after a 90-day introductory period. SENS Research Foundation is an equal opportunity employer. The job offer comes with two years contract with the possibility of an extension. We may sponsor a visa for international applicants. 

The position is available now and will be filled as soon as the qualified candidate is found. Salary is commensurate with the job title.

TO APPLY:

Interested candidates should apply by emailing a cover letter and current CV to [email protected]

COVID-19 considerations:

All employees are to follow COVID restrictions, which will lighten as our workplace is vaccinated. All employees are expected to wear PPE. Vaccinating is strongly encouraged.


Postdoctoral Fellow at the National Institute on Aging (NIA), NIH

Posted July 28, 2021 

Location: Baltimore, MD

Keywords: Mass spectrometry-based proteomics, cellular senescence, and aging biomarkers.

Position Description:

The Translational Geroproteomics Unit (TGU) is seeking diverse, highly motivated, and enthusiastic postdoctoral fellows to tackle important questions in aging biology using proteomic approaches. This is a full-time and fully funded primary research fellowship for individuals interested in leveraging mass spectrometry-based proteomics to have a translational impact on age-related diseases linked to hallmarks of aging such as cellular senescence and loss of proteostasis. Postdoctoral fellows will be mentored by Dr. Nathan Basisty, and will have access to a highly interactive, resourceful, and dynamic scientific environment with state-of-the-art instrumentation and ample opportunities for training and career development.

Qualifications: The successful candidate must have a PhD, MD, or equivalent doctoral degree.  We are looking for candidates with background and/or a strong interest in one or more of the following areas: mass spectrometry-based proteomics, characterization of PTMs, cell culture, or related fields who are passionate and self-motivated in research. Candidates with prior experience developing and performing mass spectrometry workflows, coding with R or Python, and experience with human or mouse aging models are especially encouraged to apply.

How to Apply: Please email a (i) CV, (ii) cover letter detailing research interest, experience, and career goals, and (iii) three professional references to Nathan Basisty, PhD at [email protected].

Original Job Posting - https://www.training.nih.gov/postdoc_jobs_nih/view/_31/8719/Mass_Spectrometry-Based_Proteomics_Cellular_Senescence__Aging_Biomarkers


Bioinformatics Trainer / Analyst

Posted:  July 12, 2021

Overview

Competitive salaries and full benefits including, medical, dental, and vision insurance, retirement program, vacation and sick leave, onsite cafe and much more!

The Oklahoma Medical Research Foundation (OMRF) is an independent, not-for-profit, biomedical research institute adjacent to the campus of the University of Oklahoma Health Sciences Center (OUHSC) located in Oklahoma City. OMRF investigators have internationally recognized expertise in Autoimmunity, Immunology, Genetics, Aging, Cardiovascular Disease, and Cancer. Investigators at OMRF enjoy close scientific interactions with OUHSC faculty and participate in OUHSC graduate programs. Additional information about OMRF can be found at the Oklahoma Medical Research Foundation web site: www.omrf.org.

OMRF's excellence can only be fully realized by individuals who share our commitment to diversity, equity and inclusion. Successful candidates will demonstrate commitment to these values. OMRF is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status or any other legally protected characteristic.

Responsibilities

We are seeking a bioinformatician/data analyst to support biomedical research projects and training across the institute. The hire will implement and optimize pipelines for genomic data analysis and facilitate training of individuals in the use of a variety of software, including R and Python packages, for the analysis of datasets from a variety of genomic methods, including RNAseq, ChIPseq, and scRNA-seq. The hire will also work with senior scientists and staff to organize and implement access to training materials and software.

Qualifications

Bachelor’s degree in Bioinformatics, Mathematics, Statistics, Biostatistics, Computer Science, MIS, or a relevant field and 3 years relevant experience/training in a biomedical research setting or combination of experience/education. Candidates must have prior hands-on experience in genomic data analysis using R and/or Python packages. Preference will be given to candidates who have demonstrated strong skills in project management, contribution to multiple projects, customer service, verbal and written communication, time management, organization, and experience with education/training.

To apply, visit https://apptrkr.com/2338340

OMRF’s excellence can only be fully realized by individuals who share our commitment to diversity, equity and inclusion. Successful candidates will demonstrate commitment to these values. OMRF is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status or any other legally protected characteristic.


 

Post-Doctoral Research Position Available

Posted July 7, 2021

A post-doctoral position at the Orentreich Foundation for the Advancement of Science (Cold Spring-on-Hudson, NY) is immediately available in Dr. Sailendra Nichenametla’s lab. Dr. Nichenametla investigates the mechanisms by which methionine restriction extends lifespan and confers metabolic benefits. The candidate will be working on a variety of methionine restriction projects associated with mechanisms, nutritional aspects, and prevention of diseases, including metabolic diseases, cancers, and proteostatic disorders. Responsibilities include generating data extensively from rodent models and occasionally from in vitro studies and specimens from clinical studies. The post-doc will perform experiments, data analysis, draft publication-quality manuscripts of their findings, assist in submitting grant proposals, and present work at scientific meetings.

Minimum Requirements:

  • A Ph.D. with 0-2 years of post-doctoral experience.
  • Demonstrable research experience in biomedical sciences and in two or more of the following areas/techniques: nutrition, aging, metabolism, immunohistochemistry, cell culture, molecular biology.
  • At least one paper as first author published in a peer-reviewed biomedical journal.
  • At least 1 year experience working with mice or rats.
Preferred:
  • 2-3 years’ experience working with mouse or rat models.
  • At least one paper published as first author in an aging, nutrition, or related journal.
  • HPLC experience.
  • Experience demonstrating surgery/dissection in mice/rats.

Please use this link to submit your application. You will need to upload the following files:

  • Cover letter.
  • Full curriculum vitae including education or other academic appointments, complete publication record, and research skills listed in detail.
  • PDF of the most representative publication of your previous research.