Post-Doctoral Fellow
Founded in 1946, the Oklahoma Medical Research Foundation (OMRF) is among the nation’s oldest, most respected independent, nonprofit biomedical research institutes. OMRF is dedicated to understanding and developing more effective treatments for human diseases, focusing on critical research areas such as Alzheimer’s disease, cancer, lupus, Multiple Sclerosis, and cardiovascular disease. OMRF follows an innovative cross-disciplinary approach to medical research and ranks among the nation’s leaders in patents per scientist.
Located in Oklahoma City, a city that offers a dynamic and flourishing downtown area, with low cost of living, short commute times and a diversified economy, OMRF has been voted one of the Top Workplaces since the inception of the award. This achievement has been accomplished thanks to OMRF individuals who share a unified understanding that our excellence can only be fully realized with a commitment to diversity, equity, and inclusion. Successful candidates will demonstrate commitment to these values.
We offer competitive salaries and comprehensive benefits including, medical, dental, and vision insurance, minimum 8% company retirement contribution, vacation and sick leave, paid holidays, onsite café, free onsite fitness center with access to personal trainer, free parking and much more! Relocation assistance available for those located 50 miles outside of Oklahoma City metro and out of state. Learn more about our benefits here.
OMRF is an Equal Opportunity/Affirmative Action/Veterans Employer. All qualified applicants will receive consideration for employment without regard to gender, sexual orientation, gender identity, race, color, national origin, age, religion, disability, veteran status, or any other legally protected characteristic.
Responsibilities
We are looking for a highly motivated postdoctoral research fellow to join the multidisciplinary Stout Laboratory within the Aging & Metabolism (A&M) Research Program at OMRF. The fellow will investigate how sex hormones and their receptors modulate hypothalamic neurocircuitry and the sex-specific regulation of systemic metabolism during the aging process. The successful candidate will employ a wide range of techniques including stereotaxic injection of AAVs into the brain, chemo genetic approaches (DREADD), brain imaging, single-cell transcriptomics, in vivo metabolic assessments, and a variety of cellular & molecular biology techniques. The candidate will present their data regularly in laboratory meetings, local seminars and symposiums, and will have opportunities to present their work at national conferences. A requirement of the position is that the candidate must demonstrate ethical behavior at all times, a high level of scientific rigor, and must be detail oriented and able to work independently and as part of a team.
The Stout Laboratory and A&M Research Program welcome applicants from diverse backgrounds that thrive in a highly collaborative and supportive environment. We are strongly committed to providing individualized mentoring and assistance with career advancement through the implementation of a postdoctoral mentoring committee. The A&M Research Program, which currently consists of 13 highly collaborative investigators, provides an exceptional training environment in aging biology (Geroscience). The A&M Research Program also has a strong collaborative history with faculty from the Oklahoma Center for Geroscience and Health Brain Aging at OUHSC which has resulted in a Geroscience Training Grant (T32 AG052363) that supports graduate students and postdoctoral fellows at OMRF and OUHSC. The collaborative program also houses the Oklahoma Nathan Shock Center of Excellence in Basic Biology of Aging (P30 AG050911), which provides pilot funding for junior investigators. OMRF also offers an annual grant writing course (F-troop) for graduate students and postdoctoral fellows that plan to prepare grant applications (F- or K-awards) for the NIH. The OMRF Postdoctoral Association offers additional training opportunities related to grant writing, presentation skills, and career development. The vibrant and highly collaborative environment within OMRF has resulted in the foundation being named the top large employer in the state of Oklahoma three times in the last five years.
Minimum Qualifications
The Ideal Candidate will have:
- A PhD in neuroscience or related discipline
- Prior experience with stereotaxic injection into the brain and chemogenetic approaches
- At minimum, a basic knowledge of rodent handling, rodent surgical skills, and statistical procedures
- Computer skills and prior experience with data analysis
- Prior experience writing manuscripts and be able to communicate effectively both orally and in writing
- Prior experience, or a willingness, to mentor graduate students and/or laboratory technicians
Postdoctoral Scientist: Genetic and Epigenetic Mechanisms of Transgenerational Inheritance
Marine Biological Laboratory | Woods Hole, MA
A postdoctoral research position is available in the laboratory of Dr. Kristin Gribble at the Marine Biological Laboratory, Woods Hole, MA. The Gribble lab studies the mechanisms and evolution of the biology of aging, and maternal and transgenerational effects on offspring phenotype. We use rotifers as a model system for our work. For more information about our lab’s work, see gribblebiolab.org.
Qualified applicants will have the opportunity to study the genetic and epigenetic mechanisms of maternal age effects in a novel experimental model system, focusing on how a mother’s age and physiology influence her offspring’s health and lifespan. This NSF-CAREER funded research project will use genetic, genomic, biochemical, and bioinformatic approaches to elucidate the epigenetic and genetic mechanisms of transgenerational inheritance.
Applicants should possess a Ph.D. in molecular biology, cell biology, biochemistry, genetics, bioinformatics, or a related field. Individuals with experience in bioinformatic analysis of gene expression (RNA-Seq), epigenetic regulation (ATAC-Seq, CUT&RUN, Chip-Seq, histone modifications), and/or comparative genomics are particularly encouraged to apply. The ideal candidate will have a record of scientific rigor, productivity, and creativity; the ability to work independently and as part of a team; and a strong publication record. Excellent oral and written communication skills are required. Prior experience with working with rotifers is not necessary; candidates with experience with other experimental systems are encouraged to apply.
To apply, please submit:
- a cover letter with a brief description of your research experience and how your expertise will contribute to research on the mechanisms of parental effects and transgenerational inheritance
- a CV including a list of publications
- contact information for three references
Apply here: https://recruiting.ultipro.com/MAR1033MBL/JobBoard/4c3007c3-6354-41de-a13f-d95be60d91e9/OpportunityDetail?opportunityId=b3a9dd3a-3e09-4f91-9d71-f8011e9d28dc
Questions: Contact Kristin Gribble, [email protected]
Aging Research at OMRF
The Oklahoma Medical Research Foundation (https://omrf.org/) is seeking accomplished or upcoming investigators with expertise in aging as it relates to neuroinflammation and/or neurodegeneration to join the Aging and Metabolism Research Program. Successful candidates will be expected to maintain a vigorous independent research program investigating mechanisms relevant to CNS aging associated with one or more of the following areas of special interest: inflammatory processes, circuits relevant to cognition/behavior, immune cell function, and bioenergetics. Successful candidates will receive an appointment at the Assistant, Associate, or Full Member level (Assistant, Associate, and Full Professor equivalents), dedicated research space, as well as a generous, multi-year start-up package with significant sustained salary and research support.
The Aging and Metabolism Research Program is comprised of thirteen faculty members studying a variety of diseases related to the aging process, including neurological, metabolic, musculoskeletal, and cardiovascular disorders. OMRF supports an AAALAC accredited animal facility as well as state-of-the art core facilities for imaging, -omics technologies, tissue banking, and other facilitating technologies. Additional information can be found at the Program’s website (http://omrf.org/programs/aging-and-metabolismresearch-program/). Other attractive aspects include a generous startup package, institutional support for competitive salaries, comprehensive benefits, and a collegial work environment. OMRF investigators have no formal teaching obligations but can voluntarily participate in didactic activities on campus at The University of Oklahoma Health Sciences Center (OUHSC). Overall, OMRF is committed to creating an attractive position suitable for applicants with a proven track record or exceptional potential for high-quality funded research.
OMRF is an independent, not-for-profit, biomedical research institute supporting five major interdisciplinary research programs. Our facilities are located adjacent to the campus of the University of Oklahoma Health Sciences Center (OUHSC) and the Oklahoma City VA Medical Center near downtown Oklahoma City. OMRF investigators are integral participants in OUHSC graduate programs and enjoy close scientific interactions with OUHSC and Oklahoma City VA faculty.
To apply, please send a CV, a letter describing your interest in the position, a concise research prospectus, and the names of three references via [email protected].
Visit jobs.omrf.org for more information.
EOE/AA Employer/Vet/Disabled
Postdoctoral Position (C. elegans model)
Kaya Lab (kayalab.org)
A postdoctoral position is available starting immediately in the Kaya lab at the Virginia Commonwealth University, Richmond, VA, USA. The Kaya lab will focus on both basic and translational research areas. Our newly established lab cannot take off without motivated people. Postdoctoral applicants should be independent, productive, and highly motivated to design and carry out experiments, analyze, organize, and present data in written form and to meetings, and to write papers and grants. Applicant must possess strong English and analytical skills. Salaries, stipend, and benefits are commensurate with university policy and NIH guidelines. VCU provides full health and retirement benefits for postdoctoral fellows.
REQUIRED SKILLS
The Kaya lab is establishing worm model to address questions, related to biology of aging and neurobiology. We are seeking candidates with a PhD and a strong background in neuroscience, mitochondrial biology, cellular senescence and aging or related fields who are passionate and self-motivated/independent in research. The ideal candidate must have hands on experience in worm genetics and biology, molecular cloning and other efficient genome engineering (e.g. CRISPR, MosSCI) techniques and behavioral analysis.
The possible projects include but not limited to:
1) To understand the function of essential genes in aging.
3) To understand the mechanism and the role of cytoplasmic mitochondrial DNA fragments in aging and neurodegenerative disease.
4) And other aspects of biology of aging including drug development/screening, mechanisms of dietary intervention.
Our lab provides an outstanding platform for Postdocs developing their own ideas and projects that are related to our core interests. The candidate will have access to an ample spectrum of techniques available in the lab and cutting-edge technologies to perform the experiments.
How to Apply: Interested candidates should send a cover letter summarizing their research interests, career goals and CV with a publication list and names and contact information of three references (preferably in a single PDF) to “[email protected]”.
Application Deadline Date: Open until filled.
The Kaya Lab is committed to creating a diverse, respectful environment where people of all backgrounds are welcome and can thrive. Virginia Commonwealth University is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, national origin, age, protected veteran or disabled status, or genetic information.
