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Postdoctoral Scientist
Maternal age effects: mitochondrial and epigenetic mechanisms
Marine Biological Laboratory
Woods Hole, MA
Excellent salary and benefits (significantly above NIH payscale), commensurate with experience and qualifications
Description:
A postdoctoral research position is available to study the cellular, genetic, and epigenetic mechanisms of maternal age effects on offspring health and lifespan. The project will focus on the role of mitochondrial dynamics and metabolism in maternal age effects, using molecular, bioinformatic, biochemical, and imaging techniques.
This is an NIH-funded project in the laboratory of Dr. Kristin Gribble at the Marine Biological Laboratory, Woods Hole, MA. The lab researches the biology of aging, with a focus on maternal age effects on offspring health and lifespan. We use rotifers as a model system for our work. For more information about the lab’s research, see gribblebiolab.org.
Qualifications:
Applicants should possess a Ph.D. in molecular biology, cell biology, biochemistry, genetics, bioinformatics, or a related field. The ideal candidate will have a record of scientific rigor, productivity, and creativity. Excellent oral and written communication skills are required. Knowledge of rotifer biology is not required; highly motivated individuals with experience in other model systems and with a background in bioinformatics, cell biology, biochemistry, epigenetics, and/or imaging are encouraged to apply.
Required Documents:
Please submit:
- A cover letter with a brief description of your research experience and how you will contribute to research on the mechanisms of maternal age effects on offspring,
- A CV
- Contact information for at least three references
Apply Here: https://tinyurl.com/yp2rdv52
2 Postdoctoral Researcher positions
Kapahi lab Eye Aging and neurodegeneration using flies and mammals
POSITION SUMMARY
The focus of the Kapahi Laboratory is to identify and characterize the mechanisms by which nutrients modulate aging and age-related diseases. This is being achieved by using an interdisciplinary approach combining genetic, pharmacological, biochemical, and genomic approaches in invertebrate model systems C. elegans, D. melanogaster, and mammalian cells. The broader significance of this research is to help uncover the role of nutrition in the etiology of age-related human diseases like diabetes, obesity, and neurodegeneration. You will join a highly collaborative group and the ability to be a collaborative team member is a key expectation. The position is ideal for candidates who want to transition to academia and write a K99. Strong mentorship and support to write grants will be provided.
Two Postdoctoral positions involve using bioinformatic approaches from flies and humans to study the role of circadian clocks and nutrient-responsive pathways that influence eye and neuronal degeneration using flies and conserved orthologs from humans.
QUALIFICATIONS
- Previous background in fly or bioinformatics approaches is an advantage but not essential.
- Willingness to write grants and manuscripts is a pre-requisite.
PUBLICATIONS
- Longitudinal fundus imaging and its genome-wide association analysis provide evidence for a human retinal aging clock. Sara Ahadi, Kenneth A Wilson Jr, Boris Babenko, Cory Y McLean, Drew Bryant, Orion Pritchard, Ajay Kumar, Enrique M Carrera, Ricardo Lamy, Jay M Stewart, Avinash Varadarajan, Marc Berndl, Pankaj Kapahi, Ali Bashir. Elife. 2023 Mar 28; https://elifesciences.org/articles/82364
- Dietary restriction and clock delay eye aging to extend lifespan in D. melanogaster. Hodge BA, Meyerhof GT, Katewa SD, Lian T, Lau C ,Bar S, Leung NY, Li M, Li-Kroeger D, Melov S, Schilling B, Montell C, Kapahi P. Nat Commun. 2022 Jun 7. https://www.nature.com/articles/s41467-022-30975-4
ABOUT THE BUCK INSTITUTE
Our success will ultimately change healthcare. At the Buck, we aim to end the threat of age-related diseases for this and future generations by bringing together the most capable and passionate scientists from a broad range of disciplines to identify and impede how we age. We are an independent, non-profit institution located in Marin County, CA, to increase human health span or the healthy years of life. Globally recognized as the pioneer and leader in efforts to target aging—the number one risk factor for diseases including Alzheimer’s, Parkinson’s, cancer, macular degeneration, heart disease, and diabetes— the Buck seeks to help people live better longer. We are an equal opportunity employer and strive to create an atmosphere where diversity of identity, experience, and background are welcomed, valued, and supported. Candidates who contribute to this diversity are strongly encouraged to apply.The Buck Institute has an exceptional postdoctoral research program. We offer competitive salaries, excellent benefits, a dynamic and collaborative work environment, and new state-of-the-art facilities.
TO APPLY
Interested candidates should apply online and upload a CV and cover letter including contact information for three professional references. For questions regarding this position, please email [email protected] or visit https://www.buckinstitute.org/lab/kapahi-lab/
Director, Division of Aging Biology Office of the Director
National Institute on Aging (NIA) National Institutes of Health
Department of Health and Human Services
The National Institute on Aging is seeking an innovative leader to serve as Director of its extramural Division of Aging Biology (DAB). The position is in the Office of the Director (OD), National Institute on Aging (NIA), located in Bethesda, MD and reports directly to the NIA Director.
Over the last two decades research on the biological mechanisms of aging has expanded exponentially. It is now widely acknowledged that the mechanisms of aging determine the quality of health and function, as well as contribute to the pathogenesis and modulation the progression of most chronic diseases. A greater understanding of the aging process is a fundamental step toward identifying new preventive and therapeutic strategies that can improve the human life span and reduce the burden of age-related chronic diseases, with large benefits to individuals and society.
The DAB has a fundamental role in the accomplishment of this goal with a focus on advancing research on aging by providing funding support to academic institutions across the United States through grants and programs to enable research that investigates the basic biology of aging at the molecular, cellular, and organismal levels in a variety of model systems. Through its multitude of diverse funding programs, DAB supports and ensures continuity and stability in ongoing lines of basic aging research while encouraging and facilitating the emergence of new ideas, concepts, technologies, and novel organizational models for aging research. The DAB portfolio is exceptionally broad, covering all research fields of basic aging biology, including fundamental genetic, molecular, and cellular mechanisms of aging, the study of aging in different model systems including comparative studies, search for mechanisms of longevity, and the testing of behavioral and pharmacological treatments in model systems for improvement of health-span and lifespan. Because of the strong translational nature of the topic addressed, the work of DAB is strongly connected with the research conducted by other components of NIA, as well as other NIH institutes and academic institutions with many opportunities for collaborative projects and cross-fertilization of different areas of biological, behavioral, and medical research. These goals of the DAB are implemented through extramural grants, cooperative agreements, collaborative projects, contracts, and other activities. Additional information regarding the DAB is available at the following website: https://www.nia.nih.gov/research/dab.
The Division Director serves as the scientific and administrative leader of the DAB and provides scientific expertise and strategic vision for the DAB portfolio, including identification of emerging new directions for basic aging research, support of novel technologies, and development of collaborative programs with other NIA extramural divisions, the NIA Intramural Research Program, and other NIH Institutes. The Division Director oversees all administrative operations of the DAB and has responsibility for: (1) scientific planning and strategy, (2) operational administration of the division; (3) oversight of all the division’s grants and cooperative agreement research activities; (4) budget management; and (5) working with and advising NIA senior leadership on the development and implementation of long-range strategic, scientific, facility and business plans for the division. The Division Director oversees approximately 34 scientific and administrative staff and an operating budget of $960,000 (not including personnel costs) and an extramural research portfolio of approximately $400 million.
Position Requirements: The successful candidate must have an M.D. and/or Ph.D. or equivalent degree in a relevant discipline and have extensive training and experience in research on the biology of aging or other related disciplines. The successful candidate will have experience in collaborative research as documented in publications and more generally will have a history of publications that reflect experience in the requirements of the position. In addition, the candidate must have demonstrated administrative skills in supervising scientific and administrative staff, in overseeing complex research programs, and in collaborating and enhancing partnerships in the aging research community. The candidate should also have exceptional leadership skills, including experience in developing strategic goals, working collaboratively across disciplines, budgetary planning and management, and managing human resources. Experience as an NIH grant administrator is not required. A successful candidate will also have demonstrated experience leading people while navigating change and must have a demonstrated commitment to advancing diversity, equity, inclusion and accessibility. Eligible candidates who are also active researchers may establish a small laboratory research program in the NIA IRP.
Salary/Benefits: This position will be filled under a Title 42 excepted service appointment. Salary is competitive and will be commensurate with the experience of the candidate. A recruitment or relocation bonus may be available, and relocation expenses may be paid. A full package of federal Civil Service benefits is available including: retirement, health and life insurance, long term care insurance, leave, and a Thrift Savings Plan (401K equivalent). The successful candidate may be subject to a background investigation and public financial disclosure requirements. All employees of the Federal Government are subject to the conflict-of- interest statutes and regulations, including Standards of Ethical Conduct. US Citizenship is not required.
How to Apply: Please send a cover letter, current curriculum vitae, bibliography, a vision statement a statement that addresses the specific qualification requirements listed above and a statement on diversity, equity, inclusion and accessibility (please limit statements to two pages each) to [email protected] NIA will begin accepting applications on and plans to have the position open for 60 days or until filled.
You may contact [email protected] with questions and for more information about this vacancy.
DHHS and NIH are Equal Opportunity Employers
The NIH is dedicated to building a diverse community in its training and employment programs.
Announcement Link: https://www.nia.nih.gov/news/now-hiring-join-nia-director-division-aging-biology
Geroscience
Assistant or Associate Full Professor
The Division of Geriatrics, Gerontology, and Palliative Care at the University of California, San Diego, Department of Medicine ( http://med.ucsd.edu/) is committed to academic excellence and diversity within the faculty, staff, and student body is actively recruiting academic faculty positions in Geriatrics and Palliative Care is seeking candidates for a tenured faculty position, at the rank of Assistant or Associate Professor.
The focus of this search is Geroscience, a field that seeks to understand biological mechanisms of aging to develop strategies that can delay the onset of multiple, rather than individual, age-related chronic diseases and conditions. New insights into the biological underpinnings of aging have tremendous potential to impact the development of promising prognostic tools and treatments for age-related conditions. These opportunities require interdisciplinary teams with complementary expertise in translational research, clinical trials, and human cohort studies. Successful candidates will be expected to establish a vigorous program of high-quality externally funded research. Specific focus areas include, but are not limited to: multi-omics, bioinformatics, epigenetics, and biodemography.
The Department of Medicine is a leading center for clinical care, research, and teaching. We are dedicated to translating laboratory discoveries into better methods to detect, prevent, and treat disease. As part of a research-intensive academic medical center, we offer training programs in both general internal medicine and subspecialties in an inclusive, rich educational environment. With nearly 500 full-time faculty members and over 100 academic researchers, the Department of Medicine is the largest of the distinguished departments in the UC San Diego School of Medicine. Our Geriatrics program was ranked 13th out of more than 1,500 national programs in the 2020-2021 U.S. News & World Report. Partnerships with research groups across the UCSD campus and with local research Institutes further strengthen the Division’s research program.
The successful candidate will be expected to build and maintain a high-quality, extramurally funded research program, provide service to the University and broader academic community at a level commensurate with their career stage, and contribute to a collegial and collaborative academic environment with a focus on the promotion of justice, diversity, equity, and inclusion. The successful candidate will contribute to the division journal club and in the division Grand Rounds, teaching other seminar series, and will also mentor trainees/postdocs, helping to shape and expand the University's commitment to diversity initiatives.
Candidates must have a PhD or MD/PhD with an emphasis relevant to Gerontology and/or Geroscience. Candidates must have at least two years of postdoctoral experience in Geroscience and have a track record of research excellence.
Candidates with experience in collaborative geroscience research focused on older adults are preferred. Candidates with experience creating, participating in, and/or contributing to equity and inclusion programs that increase access and success of underrepresented students and faculty in the sciences are preferred. Candidates with expertise in establishing clinical studies and utilizing biorepositories and clinical data to understand the genetic, molecular, and cellular mechanisms that underlie common chronic conditions and diseases affecting older adults are preferred
The appointment at the Associate Professor level will be based on the candidate’s background and experience. Series will include 50% Ladder Rank / 50% In-Residence with secured extramural funding or 100% Ladder Rank.
A link to full descriptions of each series is provided for your review:
The posted UC Salary scales set the minimum pay at the appointment as determined by appointment type and if applicable, rank and/or step. The base pay range for this position is $100,000 - $180,000. Salary is negotiated annually. Additional compensation may be available if the position includes membership in the Health Sciences Compensation Plan. UC Salary information can be found here: https://www.ucop.edu/academic-personnel-programs/compensation/2023-24-academic-salary-scales.html.
As a University employee, you will be required to comply with all applicable University policies and/or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.
The University of California prohibits smoking and tobacco use at all University controlled properties.
The UC San Diego Annual Security & Fire Safety Report is available online at: https://www.police.ucsd.edu/docs/annualclery.pdf. This report provides crime and fire statistics, as well as institutional policy statement & procedures. Contact the UC San Diego Police Department at (858) 534-4361 if you want to obtain paper copies of this report.
The University of California, San Diego is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, covered veteran status, or other protected categories covered by the UC nondiscrimination policy.
Director for the Wisconsin National Primate Research Center
The University of Wisconsin-Madison seeks a Director for the Wisconsin National Primate Research Center (WNPRC). The mission of the WNPRC is to increase our understanding of basic primate biology and to improve human and animal health and quality of life through research. The WNPRC is one of a network of eight unique national facilities for nonhuman primate research funded through the Office of the Director (OD) and the Office of Research Infrastructure Programs (ORIP) of the National Institutes of Health (NIH). Key areas of research supported by the Center include, but are not limited to, Infectious Disease, Neuroscience, Reproductive and Regenerative Medicine, and Energy Metabolism and Chronic Disease. The Director will provide dynamic scientific leadership and administrative oversight of the Center's ongoing scientific programs and diverse research resources for the UW-Madison and the national scientific community.
Ph.D. or other advanced degree in the biomedical sciences field is required. Candidate must be eligible for tenure at the University of Wisconsin-Madison at the full professor level. The Director will have a concurrent faculty appointment in an appropriate academic department. Please see full position listing and application instructions at: https://go.wisc.edu/9kuc3m or contact Kelly Marks at [email protected].
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